Sr Bioinformatics Scientist (MRD)

Insight Global

Full-time other-general
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Location
South San Francisco, CA, United States
Posted
June 27, 2026

Job Description

Job Description
We are looking for a Senior Bioinformatics Scientist to play a leading role in advancing cutting-edge molecular diagnostics, with a particular focus on minimal residual disease (MRD) testing. This position will drive the development and optimization of bioinformatics approaches supporting laboratory-developed assays from early concept through clinical deployment.

This role requires deep expertise in next-generation sequencing (NGS) and oncology-focused applications, including circulating tumor DNA (ctDNA) analysis. The successful candidate will lead the design of computational strategies, oversee analytical validation efforts, and ensure robust assay performance across the development lifecycle. Responsibilities include building and refining scalable analysis pipelines, applying statistical and computational methods to improve assay sensitivity and specificity, and supporting regulatory submissions through detailed documentation and validation evidence. In a...