Oligonucleotide Scientist II

Actalent

Full-time other-general
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Location
South San Francisco, CA, United States
Posted
July 25, 2026

Job Description

Job Title: Scientist II – Nucleic Acid Design and Discovery
Job Description
This on-site Scientist II role focuses on oligonucleotide discovery and synthesis within a nucleic acid design and discovery team. The position supports a growing oligonucleotide therapeutics discovery group and contributes to RNAi biology research across multiple therapeutic areas, including neuroscience, immunology, and oncology. The successful candidate applies expertise in nucleic acid chemistry to design, synthesize, purify, and characterize oligonucleotide-based therapeutics while collaborating closely with an interdisciplinary chemistry and biology team.
Responsibilities

+ Work in an oligonucleotide therapeutic drug discovery research laboratory to design, synthesize, and optimize oligonucleotide compounds.

+ Interface with project teams across therapeutic areas such as neuroscience, immunology, and oncology to help build and support a comprehensive oligonucleotide therapeutic ...