Bioassay Research Scientist II

Guidehouse

Full-time other-general
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Location
SILVER SPRING, MD, United States
Posted
July 15, 2026

Job Description

**Job Family** **:**

Scientist

**Travel Required** **:**

Up to 10%

**Clearance Required** **:**

Ability to Obtain Public Trust

Our federal client conducts regulatory science research to support the evaluation and monitoring of drug quality, safety, efficacy, and pharmaceutical quality standards.

The researcher will support laboratory-based experiments focused on NF-ÎșB activity and signal detection strategies. This work supports regulatory science objectives related to potency assay development for biological products whose mechanisms of action depend on modulation of specific subunits.

**What You Will Do** **:**

+ Perform mammalian cell culture, cell line engineering support, and maintenance of relevant human cell lines used as bioassay substrates.
+ Develop, optimize, and support qualification of cell-based bioassays capable of detecting total NF-ÎșB activity and subunit-specific NF-ÎșB activity, wit...